{"id":152,"date":"2015-02-24T02:12:23","date_gmt":"2015-02-24T02:12:23","guid":{"rendered":"http:\/\/jick.net\/wordpress\/?p=152"},"modified":"2015-03-14T14:44:25","modified_gmt":"2015-03-14T14:44:25","slug":"the-aggravo-effect","status":"publish","type":"post","link":"https:\/\/jick.ca\/?p=152","title":{"rendered":"The Nocebo Effect"},"content":{"rendered":"<p>We all know about <em>placebos<\/em>, right?\u00a0 From the Latin <i>plac\u0113b\u014d<\/i>, &#8220;I shall please&#8221;?\u00a0\u00a0When you take a placebo, you feel better because you <em>think<\/em> you&#8217;re going to feel better.\u00a0\u00a0 Of course, it&#8217;s just your imagination, right?\u00a0 You don&#8217;t <em>really<\/em> feel better; it&#8217;s all a fake, right?<\/p>\n<p>Not so much.\u00a0 A double-blind experiment on Parkinson&#8217;s patients with fluorine-18 labelled L-dopa <em>vs<\/em>. placebos showed that the placebos were effective at the specific goal of causing the brain to produce dopamine.\u00a0 The patients didn&#8217;t just &#8220;feel better&#8221;, their brains actually performed the same biochemistry that is stimulated by L-dopa.\u00a0 Think about that.\u00a0 Think <em>very carefully<\/em>.\u00a0\u00a0 These people simply thought they were getting L-dopa; they were not trained in using the mind&#8217;s power over the body.\u00a0\u00a0 What if they were?<\/p>\n<p>Yeah, yeah, we&#8217;ve all heard that woo-woo stuff before, right?\u00a0 Okay, never mind.\u00a0\u00a0 Just remember that the &#8220;Placebo Effect&#8221; is <em>real<\/em>.\u00a0\u00a0 <em>Officially<\/em> real, as in, no drug trial that fails to take it into account is considered valid by&#8230; well, <em>anyone<\/em>.\u00a0\u00a0 Now think very carefully about the <em>implications<\/em> of this established fact.<\/p>\n<p>If you believe a pill is going to make you <em>better<\/em>, it <em>will<\/em> make you better.\u00a0 Perhaps not as much better as a pill that has a direct effect on your biochemistry, but genuinely better.\u00a0\u00a0 If this is true, then the opposite might be expected to be true as well:\u00a0 if you believe a pill is going to make you <em>sick<\/em>, it <em>will<\/em> make you sick.<\/p>\n<p>And not just pills.\u00a0 Also innumerable environmental poisons, radiation, even stuff that used to be considered harmless but has now been shown (or claimed, and believed) to be detrimental to health at some concentration.\u00a0\u00a0 If you <em>believe<\/em> it will make you sick, it <em>will<\/em> make you sick. \u00a0<\/p>\n<p>This is called the &#8220;<em><strong><a href=\"http:\/\/en.wikipedia.org\/wiki\/Nocebo\">Nocebo Effect<\/a><\/strong><\/em>&#8221; (from the Latin <i>noc\u0113b\u014d<\/i>, &#8220;I shall harm&#8221;, from <i>noce\u014d<\/i>, &#8220;I harm&#8221;).\u00a0\u00a0It has also been called the &#8220;Antiplacebo Effect&#8221; or the &#8220;Negative Placebo Effect&#8221;, but that seems weaker to me.\u00a0\u00a0 I want to make a strong point about this response, not just a codicil to the literature on the Placebo Effect.<\/p>\n<p>Today there is an epidemic of allergies and autoimmune disorders, especially among young people who have spent their whole lives being told of all the ubiquitous poisons in their environment, and have never been told that the human body is incredibly resilient and robust.\u00a0\u00a0 Some of this may be genuine reactions to actual pollutants and unhealthy foods, but it must also be due in part to the <em>expectation<\/em> that everything we eat or drink or breathe is poisoning us.<\/p>\n<p>Notice that I said, &#8220;&#8230;<em>in part<\/em>&#8230;&#8221;; I didn&#8217;t say that environmental poisons don&#8217;t exist, or that all maladies are caused by bad attitudes.  But <em>what you believe is a significant contributing factor to what you experience<\/em>.  This fact is no longer the property of New Age mystics.  It is real science now.  Unfortunately, we seem to have no idea what to do about it except to excoriate anyone who disputes the notion that we are all helpless victims with no agency in our own lives.  <\/p>\n","protected":false},"excerpt":{"rendered":"<p>We all know about placebos, right?\u00a0 From the Latin plac\u0113b\u014d, &#8220;I shall please&#8221;?\u00a0\u00a0When you take a placebo, you feel better because you think you&#8217;re going to feel better.\u00a0\u00a0 Of course, it&#8217;s just your imagination, right?\u00a0 You don&#8217;t really feel better; it&#8217;s all a fake, right? Not so much.\u00a0 A double-blind<a href=\"https:\/\/jick.ca\/?p=152\" class=\"read-more\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[],"class_list":["post-152","post","type-post","status-publish","format-standard","hentry","category-rants"],"gutentor_comment":0,"_links":{"self":[{"href":"https:\/\/jick.ca\/index.php?rest_route=\/wp\/v2\/posts\/152","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/jick.ca\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/jick.ca\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/jick.ca\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/jick.ca\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=152"}],"version-history":[{"count":8,"href":"https:\/\/jick.ca\/index.php?rest_route=\/wp\/v2\/posts\/152\/revisions"}],"predecessor-version":[{"id":177,"href":"https:\/\/jick.ca\/index.php?rest_route=\/wp\/v2\/posts\/152\/revisions\/177"}],"wp:attachment":[{"href":"https:\/\/jick.ca\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=152"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/jick.ca\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=152"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/jick.ca\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=152"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}